TBLASTN 2.6.0+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Database: dbs/dm6.44.fasta 17,874 sequences; 102,739,733 total letters Query= sp|P08505|IL6_MOUSE Interleukin-6 OS=Mus musculus OX=10090 GN=Il6 PE=1 SV=1 Length=211 Score E Sequences producing significant alignments: (Bits) Value FBgn0046706 type=gene; loc=2R:4014111..4049342; ID=FBgn0046706;... 30.0 4.0 > FBgn0046706 type=gene; loc=2R:4014111..4049342; ID=FBgn0046706; name=Haspin; dbxref=FlyBase:FBgn0058080,FlyBase:FBgn0063167,GB:AA264550,GB:AABU01002748,GB:AY118897,GB_protein:AAM50757,GB:BG637897,UniProt/Swiss-Prot:P83103,INTERPRO:IPR000719,INTERPRO:IPR011009,GB_protein:EAA46104,GB_protein:EAA46104,FlyBase:FBan0040080,FlyBase:FBgn0046706,FlyBase_Annotation_IDs:CG40080,INTERPRO:IPR017441,EntrezGene:3355064,BDGP_clone:FBgn0046706,INTERPRO:IPR024604,UniProt/GCRP:P83103,DGRC_GENE:FBgn0046706,FlyAtlas:FBgn0046706,Fly-FISH:CG40080,FLYGUT:FBgn0046706,GenomeRNAi:3355064,modMine:FBgn0046706,AlphaFold_DB:P83103,DRscDB:3355064/tissue=All,EMBL-EBI_Single_Cell_Expression_Atlas:FBgn0046706,MARRVEL_MODEL:3355064,FlyAtlas2:FBgn0046706; derived_experimental_cyto=h45-h46; MD5=9fa5e147b4dbdb26a8f26f2c0ad17800; length=35232; release=r6.44; species=Dmel; Length=35232 Score = 30.0 bits (66), Expect = 4.0, Method: Compositional matrix adjust. Identities = 30/113 (27%), Positives = 46/113 (41%), Gaps = 7/113 (6%) Frame = -3 Query 21 TTTAFPTSQVRRGDFTEDTTPNRPVYTTSQVGGLITHVLWEIVEMRKELCNGNSDCMNND 80 T A SQ R D T + R Y G L +++L + L G ++ +N Sbjct 5545 TIAAVWLSQKSRNDRTGQSHHKRNSYRF*APGILFSYILRCCTSI*PSLA-GRTNVQDNK 5369 Query 81 DALAENNLKLPEIQRNDGCYQTG------YNQEICLLKISSGLLEYHSYLEYM 127 A E+ K + + C Q G Y+Q+ CL ISS L + +Y+ Sbjct 5368 TASPEHARKCSNLISSKECSQPGAPFFTPYSQQTCLQTISSQPLRLLTIPQYL 5210 Lambda K H a alpha 0.320 0.135 0.393 0.792 4.96 Gapped Lambda K H a alpha sigma 0.267 0.0410 0.140 1.90 42.6 43.6 Effective search space used: 3499799940 Query= sp|P05231|IL6_HUMAN Interleukin-6 OS=Homo sapiens OX=9606 GN=IL6 PE=1 SV=1 Length=212 Score E Sequences producing significant alignments: (Bits) Value FBgn0033121 type=gene; loc=2R:complement(6971996..6975026); ID=... 31.6 1.2 FBgn0036668 type=gene; loc=3L:16845386..16852350; ID=FBgn003666... 30.4 3.3 > FBgn0033121 type=gene; loc=2R:complement(6971996..6975026); ID=FBgn0033121; name=Cyp6u1; dbxref=FlyBase:FBgn0033121,FlyBase:FBan0003567,GB_protein:AAF57417.2,GB_protein:AAF57417.1,FlyBase_Annotation_IDs:CG3567,GB_protein:AAF57417,GB:AI541943,GB:AW944535,GB:AY069834,GB_protein:AAL39979,UniProt/Swiss-Prot:Q9V979,INTERPRO:IPR001128,INTERPRO:IPR002401,INTERPRO:IPR017972,GB_protein:AHN55948,GB_protein:AHN55947,EntrezGene:35608,UniProt/TrEMBL:A0A0B4LET2,BDGP_clone:FBgn0033121,INTERPRO:IPR036396,UniProt/GCRP:Q9V979,DGRC_GENE:FBgn0033121,EPD:Cyp6u1_1,EPD:Cyp6u1_2,FlyAtlas:FBgn0033121,Fly-FISH:CG3567,FLYGUT:FBgn0033121,GenomeRNAi:35608,modMine:FBgn0033121,AlphaFold_DB:Q9V979,DRscDB:35608/tissue=All,EMBL-EBI_Single_Cell_Expression_Atlas:FBgn0033121,MARRVEL_MODEL:35608,FlyAtlas2:FBgn0033121; derived_computed_cyto=42E1-42E1; derived_experimental_cyto=42E-42E; gbunit=AE013599; MD5=0adcc4eb636294299a9b665c8ff5a793; length=3031; release=r6.44; species=Dmel; Length=3031 Score = 31.6 bits (70), Expect = 1.2, Method: Compositional matrix adjust. Identities = 16/44 (36%), Positives = 23/44 (52%), Gaps = 4/44 (9%) Frame = +3 Query 78 CESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLLE 121 C+S K L+E+ N P A + GC SG ++ +GLLE Sbjct 1167 CKSRKRQLSEHGSNAPHPAHRPGCAVSGLRPG----QVQSGLLE 1286 > FBgn0036668 type=gene; loc=3L:16845386..16852350; ID=FBgn0036668; name=Zcchc7; dbxref=FlyBase:FBgn0036668,FlyBase:FBan0009715,FlyBase_Annotation_IDs:CG9715,GB_protein:AAF49404,GB:AI534062,GB:AI534310,GB:AW944459,GB:AY052115,GB_protein:AAK93539,GB:BG639822,UniProt/TrEMBL:Q9VVA9,INTERPRO:IPR001878,INTERPRO:IPR036875,EntrezGene:39883,UniProt/TrEMBL:Q960D5,UniProt/GCRP:Q9VVA9,DGRC_GENE:FBgn0036668,EPD:CG9715_1,FlyAtlas:FBgn0036668,Fly-FISH:CG9715,FLYGUT:FBgn0036668,GenomeRNAi:39883,iBeetle-Base:TC003588,modMine:FBgn0036668,AlphaFold_DB:Q9VVA9,DRscDB:39883/tissue=All,EMBL-EBI_Single_Cell_Expression_Atlas:FBgn0036668,MARRVEL_MODEL:39883,FlyAtlas2:FBgn0036668; derived_computed_cyto=73D1-73D1; gbunit=AE014296; MD5=14257e7a4091ecb7906068c722698ffc; length=6965; release=r6.44; species=Dmel; Length=6965 Score = 30.4 bits (67), Expect = 3.3, Method: Compositional matrix adjust. Identities = 19/48 (40%), Positives = 25/48 (52%), Gaps = 0/48 (0%) Frame = +1 Query 51 ERIDKQIRYILDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEK 98 +RID IR++ DGI++L N + KE N N KMAEK Sbjct 5719 KRIDVLIRFLRDGINSLNTNLGNAKSHYVRIKELEGMNTKNGFKMAEK 5862 Lambda K H a alpha 0.315 0.127 0.349 0.792 4.96 Gapped Lambda K H a alpha sigma 0.267 0.0410 0.140 1.90 42.6 43.6 Effective search space used: 3532205495 Query= sp|Q0GGL7|IL6_ONCMY Interleukin-6 OS=Oncorhynchus mykiss OX=8022 GN=il6 PE=2 SV=1 Length=219 Score E Sequences producing significant alignments: (Bits) Value FBgn0260995 type=gene; loc=2R:3066499..3191011; ID=FBgn0260995;... 29.3 7.1 FBgn0086906 type=gene; loc=3L:complement(2039681..2115611); ID=... 29.3 7.4 FBgn0259228 type=gene; loc=X:complement(6780790..6803593); ID=F... 28.9 9.9 > FBgn0260995 type=gene; loc=2R:3066499..3191011; ID=FBgn0260995; name=dpr21; dbxref=GB_protein:EFA98688,EntrezGene:8674044,FlyBase_Annotation_IDs:CG42596,FlyBase:FBgn0260995,GB_protein:EFA98687,GB_protein:EFA98687,INTERPRO:IPR013098,UniProt/TrEMBL:A0A0C4DHN4,INTERPRO:IPR003598,INTERPRO:IPR013783,INTERPRO:IPR013106,INTERPRO:IPR007110,INTERPRO:IPR003599,INTERPRO:IPR036179,INTERPRO:IPR037448,UniProt/GCRP:A0A0C4DHN4,FlyMine:FBgn0260995,GenomeRNAi:8674044,iBeetle-Base:TC030995,iBeetle-Base:TC004621,iBeetle-Base:TC013655,iBeetle-Base:TC014172,iBeetle-Base:TC034457,iBeetle-Base:TC009101,modMine:FBgn0260995,AlphaFold_DB:A0A0C4DHN4,DRscDB:8674044/tissue=All,EMBL-EBI_Single_Cell_Expression_Atlas:FBgn0260995,MARRVEL_MODEL:8674044,FlyAtlas2:FBgn0260995; MD5=19267264076d98052c8b554271cf64b1; length=124513; release=r6.44; species=Dmel; Length=124513 Score = 29.3 bits (64), Expect = 7.1, Method: Compositional matrix adjust. Identities = 13/41 (32%), Positives = 28/41 (68%), Gaps = 2/41 (5%) Frame = +2 Query 54 EKMIKMLVHEV--TTLRNQQFVEEFQKPVEEISSFSQHQVP 92 E+++K ++ + TTLRNQ ++ F +P+E + +F + ++P Sbjct 97766 EELMKNIIEGIPATTLRNQACIQCFSEPMEILRAFPEVRLP 97888 > FBgn0086906 type=gene; loc=3L:complement(2039681..2115611); ID=FBgn0086906; name=sls; dbxref=GB_protein:AAG22226,GB_protein:AAF47604,FlyBase:FBgn0086906,FlyBase:FBan0001915,FlyBase:FBgn0003432,FlyBase_Annotation_IDs:CG1915,FlyBase:FBgn0002186,FlyBase:FBgn0010396,FlyBase:FBgn0010850,FlyBase:FBgn0011512,FlyBase:FBgn0015898,FlyBase:FBgn0020409,FlyBase:FBgn0024279,FlyBase:FBgn0035301,FlyBase:FBgn0035302,FlyBase:FBgn0042183,GB:AA140911,GB:AA140912,GB:AA696212,GB:AA802415,GB:AA803985,GB:AA941598,GB:AA949978,GB:AB026845,GB_protein:BAA90301,GB:AF045775,GB_protein:AAC23966,GB:AF045776,GB_protein:AAC23965,GB:AF045777,GB_protein:AAC23964,GB:AF045778,GB_protein:AAC23963,GB:AF135062,GB_protein:AAF61414,GB:AF135167,GB_protein:AAF62351,GB:AF241648,GB_protein:AAG40155,GB:AF241649,GB_protein:AAF44704,GB:AF241650,GB:AF241651,GB:AI260140,GB:AI260962,GB:AI405798,GB:AJ012279,GB_protein:CAA09970,GB:AJ012280,GB_protein:CAA09971,GB:AJ238575,GB_protein:CAB43710,GB:AJ238576,GB:AJ238577,GB_protein:CAB43739,GB:AJ245406,GB_protein:CAB76253,GB:AJ271740,GB_protein:CAB93524,GB:AJ400900,GB_protein:CAB96426,GB:AJ400901,GB_protein:CAB96427,GB:AJ400902,GB_protein:CAB96531,GB:AQ025295,GB:AQ026295,GB:AQ026367,GB:AW941248,GB:AW941251,GB:AY075361,GB:AY094749,GB_protein:AAM11102,GB:BG639316,GB:BH740686,GB:BI565779,GB:BI585654,GB:BK000146,GB_protein:DAA00021,GB:CZ468524,GB:CZ469683,GB:CZ475822,GB:CZ480509,GB:CZ485690,GB:CZ488030,GB:CZ488031,GB:X72709,UniProt/Swiss-Prot:Q9I7U4,INTERPRO:IPR001452,INTERPRO:IPR003598,INTERPRO:IPR003599,INTERPRO:IPR003961,INTERPRO:IPR007110,INTERPRO:IPR013783,FlyBase:FBgn0028238,GB_protein:AGB94009,GB_protein:AGB94006,GB_protein:AGB94007,GB_protein:AGB94008,GB_protein:AGB94005,GB_protein:AGB94003,GB_protein:AGB94004,GB_protein:AGB94002,GB_protein:AGB94001,GB_protein:AGB94000,GB_protein:AGB93999,UniProt/TrEMBL:M9PDZ6,UniProt/TrEMBL:M9PEA0,UniProt/TrEMBL:M9NDX0,UniProt/TrEMBL:M9PDS8,UniProt/TrEMBL:M9PBI9,UniProt/TrEMBL:M9PBJ0,UniProt/TrEMBL:M9PDZ9,UniProt/TrEMBL:M9PDS3,UniProt/TrEMBL:M9PGZ0,UniProt/TrEMBL:M9PGY4,UniProt/TrEMBL:M9PEA9,UniProt/TrEMBL:M9PEA5,GB_protein:AFH04222,EntrezGene:44013,INTERPRO:IPR013098,BDGP_clone:FBgn0086906,INTERPRO:IPR036179,INTERPRO:IPR036028,INTERPRO:IPR036116,UniProt/GCRP:Q9I7U4,DGRC_GENE:FBgn0086906,EPD:sls_1,FlyMet:FBgn0086906,Fly-FISH:CG1915,FLYGUT:FBgn0086906,GenomeRNAi:44013,iBeetle-Base:TC030701,modMine:FBgn0086906,SignaLink:Q9I7U4,AlphaFold_DB:Q9I7U4,DRscDB:44013/tissue=All,EMBL-EBI_Single_Cell_Expression_Atlas:FBgn0086906,MARRVEL_MODEL:44013,FlyAtlas2:FBgn0086906; derived_computed_cyto=62C2-62C4; derived_experimental_cyto=62C-62C,62C1-62C2,62C1-62C2,62C1-62C1,62C1-62C3,62C-62C,61C1-61C2,62C1-62C2,62C1-62C2,68B8-68F2,62C1-62C2; gbunit=AE014296; MD5=c8348f71c7eece174672cb294edfd559; length=75931; release=r6.44; species=Dmel; Length=75931 Score = 29.3 bits (64), Expect = 7.4, Method: Compositional matrix adjust. Identities = 17/54 (31%), Positives = 27/54 (50%), Gaps = 5/54 (9%) Frame = +3 Query 102 LCSASNKEACLQEISRGLQVYQLLLQHVKAEYPQSTLLPSVTHQTTVLIGLVKD 155 L + KE +E++ L ++L + V EYP + L+P T IG +KD Sbjct 64065 LKPSKRKEKPAEELTVQLPKFRLKARMVLVEYPPAPLIPKTTD-----IGAIKD 64211 > FBgn0259228 type=gene; loc=X:complement(6780790..6803593); ID=FBgn0259228; name=C3G; dbxref=GB_protein:AGB95136,GB_protein:AGB95138,GB_protein:AGB95137,UniProt/TrEMBL:X2JIR4,GB_protein:AAO41635,GB_protein:AAF46200,GB_protein:ACL82899,GB_protein:ACL82900,GB_protein:ACL82901,GB_protein:ACL82898,GB:AA804088,GB:AF053358,GB_protein:AAC35280,GB:AQ025539,GB:AY113355,GB_protein:AAM29360,GB:BI169447,GB:BT010019,GB_protein:AAQ22488,GB:CZ470700,GB:CZ471682,GB:CZ481069,GB:CZ481070,UniProt/Swiss-Prot:O77086,INTERPRO:IPR000651,INTERPRO:IPR001895,FlyBase_Annotation_IDs:CG42328,FlyBase:FBgn0259228,FlyBase:FBgn0026145,FlyBase:FBan0014436,FlyBase:FBgn0029902,FlyBase:FBan0003126,FlyBase_Annotation_IDs:CG14436,FlyBase_Annotation_IDs:CG3126,UniProt/TrEMBL:B7Z129,UniProt/TrEMBL:B7Z130,UniProt/TrEMBL:B7Z132,UniProt/TrEMBL:B7Z131,INTERPRO:IPR023578,INTERPRO:IPR019804,GB_protein:AHN59437,UniProt/TrEMBL:M9PJ95,UniProt/TrEMBL:M9PGJ9,EntrezGene:31618,BDGP_clone:FBgn0259228,INTERPRO:IPR036964,UniProt/GCRP:O77086,INTERPRO:IPR008937,DGRC_GENE:FBgn0259228,EPD:C3G_1,EPD:C3G_2,EPD:C3G_3,EPD:C3G_4,EPD:C3G_5,FlyAtlas:FBgn0259228,FlyMet:FBgn0259228,FlyMine:FBgn0259228,Fly-FISH:CG3126,FLYGUT:FBgn0259228,GenomeRNAi:31618,iBeetle-Base:TC004461,modMine:FBgn0259228,AlphaFold_DB:O77086,DRscDB:31618/tissue=All,EMBL-EBI_Single_Cell_Expression_Atlas:FBgn0259228,MARRVEL_MODEL:31618,FlyAtlas2:FBgn0259228; derived_computed_cyto=6D1-6D2; derived_experimental_cyto=6C7-6D2; gbunit=AE014298; MD5=f1f59b8b6876b749b212c11ecadd9393; length=22804; release=r6.44; species=Dmel; Length=22804 Score = 28.9 bits (63), Expect = 9.9, Method: Compositional matrix adjust. Identities = 12/43 (28%), Positives = 23/43 (53%), Gaps = 0/43 (0%) Frame = -2 Query 57 IKMLVHEVTTLRNQQFVEEFQKPVEEISSFSQHQVPSTPPHLS 99 I ML+ + ++L+N +F + VEE ++ + P H+S Sbjct 7509 INMLISKYSSLKNFSLGADFSRHVEECVTYFTYCFPFISTHIS 7381 Lambda K H a alpha 0.313 0.128 0.361 0.792 4.96 Gapped Lambda K H a alpha sigma 0.267 0.0410 0.140 1.90 42.6 43.6 Effective search space used: 3724583315 Database: dbs/dm6.44.fasta Posted date: Feb 15, 2022 4:49 PM Number of letters in database: 102,739,733 Number of sequences in database: 17,874 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 13 Window for multiple hits: 40